Differential responses to morphine-induced analgesia in the tail-flick test
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چکیده
منابع مشابه
The effect of desmopressin infusion into dorsal raphe nucleus on pain modulation and morphine analgesia in rats tail flick reflex
Recent neuroanatomical and behavioral evidence has indicated that vasopressin (VA) increases pain threshold. The dorsal raphe nucleus (DRN) is an important nucleus in pain modulation. Anatomical studies have shown that DRN receives vasopressinergic fibers originating in the hypothalamic paraventricular nucleus. The aim of the present study was to examine the effects of intra-DRN injection of de...
متن کاملThe effect of desmopressin infusion into dorsal raphe nucleus on pain modulation and morphine analgesia in rats tail flick reflex
Recent neuroanatomical and behavioral evidence has indicated that vasopressin (VA) increases pain threshold. The dorsal raphe nucleus (DRN) is an important nucleus in pain modulation. Anatomical studies have shown that DRN receives vasopressinergic fibers originating in the hypothalamic paraventricular nucleus. The aim of the present study was to examine the effects of intra-DRN injection of de...
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There is evidence that sweeteners such as sucrose and saccharin interact with endogenous opioid systems. Further research has shown that feeding different concentrations of sucrose and saccharin alter latency in the tail-flick test. In this study, the influence of a 12-day regimen of different sweetening agents, sucrose (32%), saccharin (0.08%) and aspartame (0.16%) on morphine-induced analge...
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The aim of this study was to evaluate the effects of serine/threonine protein phosphatase (PP) inhibitors on morphine-induced antinociception in the tail flick test in mice, and on [3H]naloxone binding to the forebrain crude synaptosome fraction. Neither okadaic acid nor cantharidin (1-10000 nM) displaced [3H]naloxone from its specific binding sites, which indicates that they do not interact at...
متن کاملEvaluation of the anti-nociceptive effects of morphine, tramadol, meloxicam and their combinations using the tail-flick test in rats
The purpose of the present study was to evaluate anti-nociceptive effects of morphine, tramadol, meloxicam and their combinations in rats. Seventy male Wistar rats were divided into seven equal groups and randomly assigned to receive intraperitoneal saline (S) (control group, 1.0 mL kg-1), morphine (MO) (4.0 mg kg-1), tramadol (TR) (12.5 mg kg-1), meloxicam (ML)...
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ژورنال
عنوان ژورنال: Behavioural Brain Research
سال: 2008
ISSN: 0166-4328
DOI: 10.1016/j.bbr.2008.06.034